Edwards' music has been recognized as a major influence on the nascent UK garage genre in the United Kingdom in the mid-1990s. He became known for his intensive sampling and remixing technique that involves chopping vocal samples into micro-sized sections. Used both on his solo albums and on his remixes for other artists, this complex vocal sampling technique in some cases renders the original track almost unrecognizable.

With remixes numbering in the hundreds, some of the artists Edwards has remixed include Wildchild, St. Germain, Benjamin Diamond, Justice, Klaxons and Dimitri from Paris. Edwards co-produced and performed vocals on the Daft Punk song “Face to Face” from the album Discovery. Edwards worked again with Daft Punk, co-writing, co-producing and contributing vocals to the song “Fragments of Time” from their 2013 album Random Access Memories, for which he won a Grammy.