Thom Green formed indie-rock band ∆ (alt-J) in 2007 with fellow Leeds University students Gwil Sainsbury, Joe Newman, and Gus Unger-Hamilton. He drummed on An Awesome Wave, This Is All Yours and RELAXER.

In August 2016 he released his own album, High Anxiety, recorded whilst touring with Alt-J.

Green suffers from a rare genetic disease called Alport Syndrome which causes hearing loss and kidney failure. As a result, he is now about 80 percent deaf and had to receive a kidney transplant as a teenager.