Morphine is an alternative rock band based out of Cambridge, Massachusetts. The band was formed by Mark Sandman, Dana Colley and Jerome Dupree. What caught the attention of most people was the simplicity of the instruments used by the band, a two-string slide bass and vocals by Sandman, a saxophone played by Colley and drums played by Dupree. The group packed a tremendous punch and produced unbelievable sound for such basic instruments.

Morphine were known for their bluesy, Jazz-sounding songs that were unique in their own way. Sadly in rehearsal for a show on July 3, 1999 in Palestrina, Italy, Sandman collapsed into cardiac arrest and passed away.

Morphine took a break for years but started touring together in 2014, going under the name Vapors Of Morphine with new band member Jeremy Lyons.