Byron Simpson, better known as Guilty Simpson is a rapper from Detroit, Michigan. He was signed to Stones Throw Records and is also known for being a favorite of the late producer J Dilla. His debut album, Ode to the Ghetto, includes production from J Dilla, as well as other frequent collaborators Madlib and Black Milk.

Along with Sean Price, Guilty Simpson and Black Milk form the rap trio Random Axe. Simpson is also affiliated with the Detroit hip hop collective Almighty Dreadnaughtz.